FAQ List - Applications Section

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Which applications are available?

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  • Viability and cell count
  • Cell cycle
  • Annexin V
  • Caspase
  • Mitochondrial potential
  • Cell Vitality
  • DNA Fragmentation
  • GFP Transfection Efficiency
  • FlexiCyte (user adaptable protocols)

Read more about the applications here.

Will new assays be developed?

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Yes, we are continuously developing new assays. They will be released as they are perfected.

Can I develop a new assay?

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Yes. The FlexiCyte module enables the user to create user adaptable protocols. Read more here.

Which cell types are validated?

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At the moment we can analyze mammalian, yeast, insect and fish cells.

Is there a need for calibration when changing between cell types?

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No the NC-3000 applications have been validated for a range of different cell types and no calibration is needed in-between different cell lines. In fact no calibration at all is necessary for the user.

Which mammalian cell lines can be used?

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All the mammalian cell lines we have tested have been suited for analysis by the NC-3000. This includes but are not limited to; HEK, CHO, MCF-7, NS0 and PER.C6.

Sample volume?

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Depending on whether you use a cassette, A2 slide or A8 slide the sample consumption is either 60µl, 30µl or 8µl. The analyzed volume is 1µl.

What is the optimal range of cell concentration?

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The optimal range is 5x104 – 1x107 cells/ml.



What is the average analysis time?

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The analysis time is typically between 15-60 seconds.

Can the NC-3000 distinguish between G2 cells and 2 G1 double cells?

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The NC-3000 is capable of distinguishing between G2 cells and two G1 cells which are in close spatial connection by way of our software algorithm which recognizes the two G1 cells as being two distinct cells and therefore distributes the intensity signal of the double cells evenly.

What happens when you analyze polyploids?

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As with double cells there is no problem working with 1n, 2n ….. Xn cell lines. The software quantifies the intensities and plots its relative to its neighbors and since all the cells are polyploids of a given level the software will have no trouble analyzing the cells.